ONCOMETABOLITE LACTATE ENHANCES BREAST CANCER PROGRESSION BY ORCHESTRATING HISTONE LACTYLATION-DEPENDENT C-MYC EXPRESSION

Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression

Due to the enhanced glycolytic rate, cancer cells generate lactate copiously, subsequently promoting Hair Spray the lactylation of histones.While previous studies have explored the impact of histone lactylation in modulating gene expression, the precise role of this epigenetic modification in regulating oncogenes is largely unchartered.In this stud

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Dissection of affinity captured LINE-1 macromolecular complexes

Long Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic element active in human genomes.L1-encoded ORF1 and ORF2 proteins bind L1 RNAs, forming ribonucleoproteins (RNPs).These RNPs interact with diverse host proteins, some Wing Chair repressive and others required for the L1 lifecycle.Using differential affinity purifications, quantita

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Dataset on body weight and length of rainbow trout, Oncorhynchus mykiss, fed with dihydroquercetin, arabinogalactan or a mixture of both in an aquaria experiment

The use of natural dietary supplements in aquaculture has received a great deal of attention in recent years.This article provides data describing body weight and length of Sculpting pasta rainbow trout juveniles fed with natural dietary supplements dihydroquercetin, arabinogalactan or a mixture of both in an aquaria experiment.Before feeding trial

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